Once you have followed the instructions in the Installation Guide, you can begin setting up settings profiles for your users. You may refer to 'Create Permission Sets' section available in Installation Guide (Page # 25) for setting up user permissions and assigning users to profiles.
Once you have accessed the permission sets page, you can click the "Add New" button to create a new settings profile. If the "Add New" button is not there, you will first need to click the "Load Record Type" button. Please note that the load record type process could take a few hours to complete. You will want to make sure that you do not close your Salesforce session while that process is running.